You asked: What is this type of chromosomal alteration called?

What is this type of chromosome alteration called?

A translocation occurs when a piece of one chromosome breaks off and attaches to another chromosome. This type of rearrangement is described as balanced if no genetic material is gained or lost in the cell. If there is a gain or loss of genetic material, the translocation is described as unbalanced .

What are chromosomal alterations?

Genetic alternations include chromosomal abnormalities and gene mutations. Chromosomal abnormalities generally arise during cell division. They can be numeric, involving the number of chromosomes, or structural, involving the atypical configuration of one or more chromosomes.

What is an alteration in a gene called?

Learn more. A gene variant is a permanent change in the DNA sequence that makes up a gene. This type of genetic change used to be known as a gene mutation, but because changes in DNA do not always cause disease, it is thought that gene variant is a more accurate term.

What are the types of chromosomal structural mutations?

Chromosome structure mutations can be one of four types:

  • deletion is where a section of a chromosome is removed.
  • translocation is where a section of a chromosome is added to another chromosome that is not its homologous partner.
  • inversion is where a section of a chromosome is reversed.
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What are some examples of chromosomal mutations?

Some of the most common chromosomal abnormalities include:

  • Down’s syndrome or trisomy 21.
  • Edward’s syndrome or trisomy 18.
  • Patau syndrome or trisomy 13.
  • Cri du chat syndrome or 5p minus syndrome (partial deletion of short arm of chromosome 5)
  • Wolf-Hirschhorn syndrome or deletion 4p syndrome.

What are the different types of changes that result in alteration in chromosome number?

Changes in chromosome number are of two basic types: changes in whole chromosome sets (resulting in a condition of aberrant euploidy) and changes in parts of chromosome sets (resulting in aneuploidy).

How do chromosomal alterations occur?

Some chromosomal conditions are caused by changes in the number of chromosomes. These changes are not inherited, but occur as random events during the formation of reproductive cells (eggs and sperm). An error in cell division called nondisjunction results in reproductive cells with an abnormal number of chromosomes.