What is a high mitotic index?
An elevated mitotic index indicates more cells are dividing. In cancer cells, the mitotic index may be elevated compared to normal growth of tissues or cellular repair of the site of an injury.
Which tissue has the highest rate of mitosis?
Skin cells, hair follicles and the cells lining our intestines (epithelial cells) all have high rates of mitosis as these tissues constantly need to be replaced. In plants growth occurs largely at the shoot and root tips. These cells have much higher rates of mitosis than the rest of the plant.
What is mitotic index used for?
The mitotic index (percentage of cells in mitosis at any time) provides a measure of the capacity of cells to divide and of the rate of cell division. It is used to identify the sites of growth within a tissue and to determine which cell types are dividing.
How many mm2 is HPF?
The most recent revision of the American Joint Committee on Cancer melanoma staging system now incorporates MR and specifies that MR should be reported as mitoses per mm2, with a conversion factor of 1 mm2 equaling 4 hpf.
What do you mean by mitotic index?
Listen to pronunciation. (my-TAH-tik IN-dex) In a population of cells, the ratio of the number of cells undergoing mitosis (cell division) to the number of cells not undergoing mitosis.
What is considered a high mitotic rate in melanoma?
Melanomas with very high mitotic activity (≥10 mitoses/mm2) were predominantly thick and ulcerated nodular tumor subtypes. Conversely, the superficial spreading melanoma subtype, features of regression, and the presence of preexisting nevi were found to be characteristic of lesions with sparse mitotic activity.
Which zone has the most mitotic activity?
Why? The end has the most mitotic activity.
What is the mitotic index of onion root?
The mitotic index of the onion root tip 1 and 2 was calculated and recorded in table 3. The mitotic index was predicted to be huge due to observing the root region of division of the root but was actually under 50% with a 26% value for both root tips.
Which parameters can influence plant mitotic index?
Other factors that may affect the mitotic rate are salinity, temperature, mineral limiting factors, pH, roundworms, soil bac teria or fungus, other plant hormones, amount of light, acetaminophen, aspirin, ibuprofen, vitamins and minerals, heavy metals, antibiotics, and certain plant competitors that excrete inhibiting …