Three Functional Elements Are Required for Replication and Stable Inheritance of Chromosomes
Which type of mutation occurs during mitosis?
Somatic mutations occur in non-reproductive cells; they are passed to daughter cells during mitosis but not to offspring during sexual reproduction. As mentioned, sickle-cell anemia is the result of a change in a single nucleotide, and it represents just one class of mutations called point mutations.
How do mutations occur during cell division?
Mutation. A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses.
During which process do mutations occur?
A mutation is a change that occurs in our DNA sequence, either due to mistakes when the DNA is copied or as the result of environmental factors such as UV light and cigarette smoke. Mutations can occur during DNA replication if errors are made and not corrected in time.
What can go wrong during mitosis?
Mistakes during mitosis lead to the production of daughter cells with too many or too few chromosomes, a feature known as aneuploidy. Nearly all aneuploidies that arise due to mistakes in meiosis or during early embryonic development are lethal, with the notable exception of trisomy 21 in humans.
How do mutations occur in mitosis?
Mutations can result from the insertion, deletion, or substitution of one or a few nucleotides in a gene sequence. Small changes of this sort usually result from errors in DNA replication prior to cell division or from errors in the DNA repair that occurs in response to DNA damage.
During which stage of cell division did the mutation likely occur?
if it is a gene mutation then it is during the S phase, and if it is a chromosome mutation, then during metaphase or anaphase.
Where do mutations occur in the cell?
Acquired (or somatic) mutations occur in the DNA of individual cells at some time during a person’s life. These changes can be caused by environmental factors such as ultraviolet radiation from the sun, or can occur if a mistake is made as DNA copies itself during cell division.
What phase of cell cycle controls gene mutations?
One of the critical processes monitored by the cell cycle checkpoint surveillance mechanism is the proper replication of DNA during the S phase. Even when all of the cell cycle controls are fully functional, a small percentage of replication errors (mutations) will be passed on to the daughter cells.