Humans are most closely related to the great apes of the family Hominidae. This family includes orangutans, chimpanzees, gorillas, and bonobos. Of the great apes, humans share 98.8 percent of their DNA with bonobos and chimpanzees. Humans and gorillas share 98.4 percent of their DNA.
In general, however, the overall conclusion is that most genes would share about 98.5 percent similarity. The actual protein sequences encoded by these genes would then typically be slightly more similar to one another, because many of the mutations in the DNA are “silent” and are not reflected in the protein sequence.
The researchers found the physiology of the two is 84 per cent similar at the genetic level.
What are humans genetically closest to?
The chimpanzee and bonobo are humans’ closest living relatives. These three species look alike in many ways, both in body and behavior.
It’s not just history linking us together, it’s DNA too. At least one shark species carries several genes that are almost identical to those found in humans. Researchers have identified that 154 genes in humans have comparable matches in elephant sharks, mice, and dogs.
The DNA in alligators, crocodiles and gharials is about 93 percent identical across the genome. By comparison, a human shares about 93 percent of his or her DNA with a macaque. A Texas Tech University biologist led a team of more than 50 scientists who mapped the genomes of three crocodilians.
As a result, we share roughly 90 percent of our DNA with mice, dogs, cattle, and elephants.
Also, the study finds that approximately one-fourth of the human genome is shared with both rats and mice. That’s approximately 700 megabases of DNA shared by all three animals.