Why do SNP have two alleles?
( http://en.wikipedia.org/wiki/Single-nucleotide_polymorphism ). The majority of SNPs have two alleles, which represent a substitution of one base for another. The SNP occurs at each allele of an individual may be different. If the SNP occurs more frequently in the general population, it is called “major” allele.
What is a difference between a SNP and a genetic mutation?
Mutation is any kind of variation in the genome, including addition, deletion, duplication, substitution and… .But SNPs are just single-nucleotide substitutions of one base for another that occur in more than one percent of the general population. And frequency of mutation is less than one percent.
Which is an example of a SNP?
An example of an SNP is the substitution of a C for a G in the nucleotide sequence AACGAT, thereby producing the sequence AACCAT. The DNA of humans may contain many SNPs, since these variations occur at a rate of one in every 100–300 nucleotides in the human genome.
What is a SNP in genetics?
Listen to pronunciation. (snip) A DNA sequence variation that occurs when a single nucleotide (adenine, thymine, cytosine, or guanine) in the genome sequence is altered and the particular alteration is present in at least 1% of the population. Also called single nucleotide polymorphism.
What is the difference between somatic mutation and SNPs?
The same point mutation can occur after the the organism has developed, then it would be considered somatic. Both are changed with respect to the reference genome, but SNPs occur in population and somatic mutations are detected in one individual.
What type of mutation is SNP?
Single nucleotide polymorphisms (SNPs) are polymorphisms that are caused by point mutations that give rise to different alleles containing alternative bases at a given position of nucleotide within a locus.
How can a SNP affect a protein?
A SNP is a change in 1 nucleotide or base-pair within a codon in the DNA. Depending on its location, a SNP may alter how a gene is transcribed or the amino acid sequence for the protein being made, ultimately causing a change in activity of that protein.