What happens when a chromosome condenses?
Several DNA binding proteins catalyze the condensation process, including cohesin and condensin. Cohesin forms rings that hold the sister chromatids together, whereas condensin forms rings that coil the chromosomes into highly compact forms. The mitotic spindle also begins to develop during prophase.
What does it mean when chromatin condense into chromosomes?
During prophase, the complex of DNA and proteins contained in the nucleus, known as chromatin, condenses. The chromatin coils and becomes increasingly compact, resulting in the formation of visible chromosomes. Chromosomes are made of a single piece of DNA that is highly organized.
What does a centrosome look like?
Centrosomes are made up of two, barrel-shaped clusters of microtubules called “centrioles” and a complex of proteins that help additional microtubules to form. This complex is also known as the microtubule-organizing center (MTOC), since it helps organize the spindle fibers during mitosis.
Why do chromosomes have to condense during mitosis?
This condensation is needed to allow the chromosomes to move along the mitotic spindle without becoming tangled or broken during their distribution to daughter cells. DNA in this highly condensed state can no longer be transcribed, so all RNA synthesis stops during mitosis.
Why is it important for DNA to condense?
During mitosis, the chromosomes condense so that each chromosome is a distinct unit. Prior to mitosis, the cell copies its DNA so that it contains two copies of each chromosome. … Condensing the DNA into tightly packed chromosomes makes the process of chromosome alignment and separation during mitosis more efficient.