Is SS a bad genotype?
SS and AC are the abnormal genotypes or the sickle cells. We all have a specific pair of these hemoglobin in our blood which we inherited from both parents.
What does SS mean in sickle cell?
Sickle Cell Anemia (SS): When a child inherits one substitution beta globin genes (the sickle cell gene) from each parents, the child has Sickle Cell Anemia (SS). Populations that have a high frequency of sickle cell anemia are those of African and Indian descents.
Is SS better than SC?
Patients with Hb SC disease live longer than patients with Hb SS and have fewer painful episodes, but this disorder is associated with considerable morbidity and mortality, especially after age 30.
Can SS genotype live long?
However, a new report published online today in Blood, the Journal of the American Society of Hematology (ASH), shows that some people with mildly symptomatic SCD may live long lives with proper management of the disease, including strong family support and strict adherence to medication and appointments.
How long can ss patient live?
A published case study reports that patients with mildly symptomatic sickle cell disease (SCD) can exceed the U.S. median life expectancy of 47 years for patients with the disease if it is managed properly.
What is the best genotype?
Best genotype for marriage
- AA and AA – excellent.
- AA and AS – good.
- AS and AA – normal.
- AS and AS – bad.
- AS and SS – really bad.
- SS and SS – the worst.
Is SC and SS the same?
Hemoglobin SC disease is the second most common type of sickle cell disease. It occurs when you inherit the Hb C gene from one parent and the Hb S gene from the other. Individuals with Hb SC have similar symptoms to individuals with Hb SS. However, the anemia is less severe.
What is the sickness of SS genotype?
Hemoglobin SS disease is the most common and most severe type of sickle cell disease. It occurs when you inherit the hemoglobin S gene mutation from both parents. In this type, the body only produces hemoglobin S. This type is often called “sickle cell anemia.”
What are the symptoms of SS genotype?
Early signs of Hb SS include:
- Sleeping longer or more often.
- Difficulty breathing.
- Pain or swelling in the hands or feet.
- Cold hands or feet.
- Pale skin.
Can AA and SS marry?
AC is rare whereas AS and AC are abnormal. Compatible genotypes for marriage are: AA marries an AA. … And definitely, SS and SS must not marry since there’s absolutely no chance of escaping having a child with the sickle cell disease.
What should sickle cell patients avoid?
avoid very strenuous exercise – people with sickle cell disease should be active, but intense activities that cause you to become seriously out of breath are best avoided. avoid alcohol and smoking – alcohol can cause you to become dehydrated and smoking can trigger a serious lung condition called acute chest syndrome.
What blood type carries sickle cell?
Like most genes, individuals inherit one from each parent. Examples: If one parent has sickle cell anemia (SS) and the other parent has normal (AA) blood, all of the children will have sickle cell trait.