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## How do you calculate p-value in Hardy Weinberg?

To calculate the allelic frequencies we simply **divide the number of** S or F alleles by the total number of alleles: 94/128 = 0.734 = p = frequency of the S allele, and 34/128 = 0.266 = q = frequency of the F allele.

## What is P in the Hardy-Weinberg equilibrium?

Hardy-Weinberg Equations and Analysis. According to the Hardy-Weinberg principle, the variable p often **represents the frequency of a particular allele, usually a dominant one**. For example, assume that p represents the frequency of the dominant allele, Y, for yellow pea pods.

## How do you calculate p and q allele frequencies?

To determine q, which is the frequency of the recessive allele in the population, simply **take the square root of q ^{2}** which works out to be 0.632 (i.e. 0.632 x 0.632 = 0.4). So, q = 0.63. Since p + q = 1, then p must be 1 – 0.63 = 0.37.

## How do you compute the p-value?

The p-value is calculated using the sampling distribution of the test statistic under the null hypothesis, the sample data, and the type of test being done (lower-tailed test, upper-tailed test, or two-sided test). The p-value for: a lower-tailed test is specified by: **p-value = P(TS ts | H _{} is true) = cdf(ts)**

## How do you calculate P and Q?

We can calculate the values of p and q, in a representative sample of individuals from a population, by **simply counting the alleles and dividing by the total number of alleles examined**. For a given allele, homozygotes will count for twice as much as heterozygotes.

## What do PQ p2 2pq and q2 represent?

p2 +2pq + q2 = 1 Where p2 represents the frequency of the homozygous dominant genotype, q2 represents **the frequency of the recessive genotype** and 2pq is the frequency of the heterozygous genotype.