Is a high mitotic index bad?
Conclusion. A high mitotic rate in a primary melanoma is associated with a lower survival probability. Among the independent predictors of melanoma-specific survival, mitotic rate was the strongest prognostic factor after tumor thickness.
What is the significance of mitotic index?
The mitotic index (percentage of cells in mitosis at any time) provides a measure of the capacity of cells to divide and of the rate of cell division. It is used to identify the sites of growth within a tissue and to determine which cell types are dividing.
What are reasons for the increase in the mitotic index?
Tm-; mitotic index, the percentage of cells in division, is known to increase in actively dividing cell populations which have been treated with colchicine. This increase, which has been frequently described 1 , is detected in the first few hours of treatment and is caused by the accumulation of cells at metaphase.
What is considered a normal mitotic index?
less than 1 per square millimeter. 1 to 4 per square millimeter.
What is considered a high mitotic rate?
The ratio of men to women in the highest mitotic rate group (≥10/mm2) was 2.2:1, and 45% of these patients were 70 years or older. The presence of solar keratosis was also associated with higher mitotic rate (OR, 1.3; 95% CI, 1.1-1.6).
What would you expect to happen to the mitotic index of a population of cells that loses the ability to divide as they mature?
What would happen to the mitotic index to a population of cells that mature? The mitotic index would drop as the loss of their ability to divide will result in a smaller ratio of cells in mitosis to overall cells.
Which parameters can influence plant mitotic index?
Other factors that may affect the mitotic rate are salinity, temperature, mineral limiting factors, pH, roundworms, soil bac teria or fungus, other plant hormones, amount of light, acetaminophen, aspirin, ibuprofen, vitamins and minerals, heavy metals, antibiotics, and certain plant competitors that excrete inhibiting …
What is the role of mitosis in the growth of a plant?
Like other multicellular organisms, plants grow through a combination of cell growth and cell division. Cell growth increases cell size, while cell division (mitosis) increases the number of cells. As plant cells grow, they also become specialized into different cell types through cellular differentiation.